Beneath situations of reduced CB1R density, THC antagonises endogenous agonists possessing higher receptor efficacy than THC19. THC also allosterically modulates opioid receptors20, which can give supplemental indirect routes for altering dopamine transmission21. Additionally, THC has psychoactive metabolites with CB1R affinity, further complicating the analyses of receptor binding st... https://accidentliabilitysupport33320.bloggadores.com/32274160/delta-8-thc-things-to-know-before-you-buy