Here, we demonstrate that conolidine, a pure analgesic alkaloid Utilized in regular Chinese drugs, targets ACKR3, thereby providing further evidence of a correlation among ACKR3 and agony modulation and opening different therapeutic avenues to the procedure of chronic agony. We demonstrated that, in contrast to classical opioid receptors, ACKR3 https://juniusw294pwb4.ouyawiki.com/user