Substitution at R3 using a halogen or alkoxy group (74f–74i) led to a slight boost in cellular potency With all the halide analogs (74g–h) showing best the potency within the group. Even more optimization brought about the discovery of 74i–j, with 74k as probably the most Lively compound while in https://indazole-products77642.win-blog.com/11762192/indazole-3-carboxamide-an-overview